Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511093 | 1.00 | TAAR1 (0.59) | TAAR1PKMAOC3LMNAHKDC1 | |
| SCHEMBL8157573 | 0.88 | AOC3 (0.48) | TAAR1AOC3LMNAHKDC1SLC6A2 | |
| SCHEMBL8091005 | 0.87 | TAAR1 (0.55) | TAAR1PKMAOC3LMNAHKDC1 | |
| SCHEMBL2353775 | 0.85 | TAAR1 (0.48) | TAAR1PKMAOC3LMNAHKDC1 | |
| SCHEMBL1132061 | 0.85 | TAAR1 (0.53) | TAAR1PKMHKDC1OPRM1HTR2A | |
| SCHEMBL10831187 | 0.84 | TAAR1 (0.47) | TAAR1AOC3LMNAHKDC1RIPK1 | |
| SCHEMBL2464535 | 0.84 | TAAR1 (0.47) | TAAR1AOC3LMNAHKDC1RIPK1 | |
| SCHEMBL3267049 | 0.84 | TAAR1 (0.52) | TAAR1PKMOPRM1KCNH2HTR2A | |
| SCHEMBL12803686 | 0.83 | TAAR1 (0.45) | TAAR1AOC3LMNAHKDC1RIPK1 | |
| SCHEMBL22029995 | 0.83 | TAAR1 (0.45) | TAAR1AOC3LMNAHKDC1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126836-A4 | BENZAMIDE POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-1126836-A1 | BENZAMIDE POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025774-A1 | BENZAMIDE POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |