SCHEMBL7511097

SCHEMBL7511097

COCC1CN(c2ccc(O)cc2)C(=O)O1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 13/20 0.62
MAOA P21397 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9463574 1.00 GRM2 (0.62) GRM2MAOA
SCHEMBL7511100 1.00 GRM2 (0.62) GRM2MAOA
SCHEMBL9204446 0.87 GRM2 (0.49) GRM2MAOA
SCHEMBL9211870 0.87 GRM2 (0.49) GRM2MAOA
SCHEMBL9211629 0.87 GRM2 (0.49) GRM2MAOA
SCHEMBL21581720 0.87 GRM2 (0.66) GRM2MAOA
SCHEMBL9482679 0.86 GRM2 (0.63) GRM2
SCHEMBL9463129 0.86 GRM2 (0.53) GRM2MAOA
SCHEMBL9463295 0.86 GRM2 (0.63) GRM2
SCHEMBL9482831 0.86 GRM2 (0.53) GRM2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0736606-B1 Process for the enzymatic preparation of intermediates for the synthesis of befloxatone SANOFI SYNTHELABO (FR) 2002-01-02 EP disclosed
US-5716841-A Process for the resolution of ethyl 4,4,4-trifluoro-3(R)-hydroxybutanoate using lipase from candida SYNTHELABO (FR) 1998-02-10 US disclosed
EP-0736606-A1 Process for the enzymatic preparation of intermediates for the synthesis of befloxatone SYNTHELABO (FR) 1996-10-09 EP disclosed
US-5264443-A Psychotropic drugs, antidepressants and anxiolytic agents DELALANDE S.A. (FR) 1993-11-23 US disclosed
US-5235063-A Acetal derivatives of 3-aryl-2-oxazolidine; antidepressants DELALANDE S.A. (FR) 1993-08-10 US disclosed
US-5196543-A Antidepressants, tranquilizers DELALANDE S.A. (FR) 1993-03-23 US disclosed
US-5171747-A Anxiolytic agents, antidepressants DELALANDE S.A. (FR) 1992-12-15 US disclosed
US-5036091-A Psychotropic drugs DELALANDE S.A. (FR) 1991-07-30 US disclosed
US-5036090-A Antidepressants DELALANDE S.A. (FR) 1991-07-30 US disclosed
US-4517197-A ANTIDEPRESSANTS DELALANDE S.A. (FR) 1985-05-14 US disclosed