SCHEMBL75116

SCHEMBL75116

C=CC(=O)Oc1ccc(-c2ccc(C(=O)OCC(C)CC)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.59
THRB P10828 2/20 0.47
SLC1A5 Q15758 1/20 0.41
ADRB2 P07550 6/20 0.40
ADRB1 P08588 6/20 0.40
ADRB3 P13945 6/20 0.40
GAA P10253 1/20 0.40
ACHE P22303 1/20 0.40
ELANE P08246 1/20 0.38
TSHR P16473 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 1/20 0.37
PRSS1 P07477 1/20 0.37
ACR P10323 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408478 0.88 MAPT (0.52) MAPTTHRBADRB2ADRB1ADRB3
SCHEMBL18257469 0.87 MAPT (0.51) MAPTTHRBSLC1A5ADRB2ADRB1
SCHEMBL10333528 0.86 MAPT (0.50) MAPTTHRBADRB2ADRB1ADRB3
SCHEMBL9489638 0.86 MAPT (0.50) MAPTTHRBADRB2ADRB1ADRB3
SCHEMBL9488682 0.86 MAPT (0.50) MAPTTHRBADRB2ADRB1ADRB3
SCHEMBL9151915 0.86 MAPT (0.50) MAPTTHRBADRB2ADRB1ADRB3
SCHEMBL9455770 0.86 MAPT (0.50) MAPTTHRBADRB2ADRB1ADRB3
SCHEMBL10409031 0.86 MAPT (0.50) MAPTTHRBADRB2ADRB1ADRB3
SCHEMBL8956806 0.86 MAPT (0.78) MAPTSLC1A5ADRB2ADRB1ADRB3
SCHEMBL9493539 0.86 MAPT (0.78) MAPTSLC1A5ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
EP-2110390-B1 POLYMERIZABLE COMPOSITION ADEKA CORP (JP) 2014-07-02 EP disclosed
EP-2325168-B1 POLYMERIZABLE OPTICALLY ACTIVE IMIDE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND ADEKA CORP (JP) 2014-03-19 EP disclosed
US-8512597-B2 Polymerizable optically active imide compound and polymerizable composition containing the compound ADEKA CORPORATION (JP) 2013-08-20 US disclosed
US-8512597-B2 Polymerizable optically active imide compound and polymerizable composition containing the compound ADEKA CORPORATION (JP) 2013-08-20 US disclosed
US-8197710-B2 Polymerizable compound and polymerizable composition ADEKA CORPORATION (JP) 2012-06-12 US disclosed
US-8139189-B2 Liquid crystal display having particular oblique vapor deposition-alignment layer with ferroelectric liquid crystal DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-20 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed
US-8130358-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-06 US disclosed
US-20090294730-A1 POLYMERIZABLE COMPOSITION ADEKA CORPORATION (JP) 2009-12-03 US disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 US disclosed
EP-2067796-A1 POLYMERIZABLE COMPOUND AND POLYMERIZABLE COMPOSITION Adeka Corporation (JP) 2009-06-10 EP disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 US disclosed
US-20090021675-A1 Liquid Crystal Display Device, Manufacturing Method Thereof, and Color Filter Substrate IPS ALPHA SUPPORT CO., LTD. (JP) 2009-01-22 US disclosed
US-20080291377-A1 Liquid Crystal Display Device and Manufacturing Method Thereof HITACHI DISPLAYS, LTD. (JP) 2008-11-27 US disclosed
US-20080074588-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF MAGNOLIA PURPLE CORPORATION (JP) 2008-03-27 US disclosed
US-20070026165-A1 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2007-02-01 US disclosed
US-20070026165-A1 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 MAPT 1343/4885THRB 3657/4885SLC1A5 2268/4885
US-20090294730-A1 POLYMERIZABLE COMPOSITION SCO2, NAT1, CORO1C MAPT 3827/4885THRB 985/4885SLC1A5 2351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.