Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.59 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319049 | 0.92 | CHRM1 (0.70) | SLC18A3CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL8863397 | 0.92 | CHRM1 (0.76) | SLC18A3CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL8863399 | 0.92 | CHRM1 (0.76) | SLC18A3CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL8863438 | 0.92 | CHRM1 (0.76) | SLC18A3CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL3142425 | 0.85 | CHRM1 (0.81) | SLC18A3CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL4084782 | 0.85 | CHRM1 (0.76) | SLC18A3CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL342295 | 0.84 | CHRM1 (0.62) | SLC18A3CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL16455979 | 0.84 | CHRM1 (0.62) | SLC18A3CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL22605478 | 0.84 | CHRM1 (0.62) | SLC18A3CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL2604450 | 0.84 | CHRM1 (0.62) | SLC18A3CHRM1CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196391-A1 | BENZIMIDAZOLONE DERIVATIVES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001005770-A1 | BENZIMIDAZOLONE DERIVATIVES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-25 | — | — | WO | disclosed |