SCHEMBL7511985

SCHEMBL7511985

CCCCCC1CCC(C(=O)O)(c2ccc(OCCC)cc2)CC1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.67
TSHR P16473 2/20 0.67
MEN1 O00255 1/20 0.67
GPR119 Q8TDV5 6/20 0.45
ITGB3 P05106 3/20 0.43
ITGA2B P08514 3/20 0.43
TET3 O43151 1/20 0.43
FBXL19 Q6PCT2 1/20 0.43
CXXC5 Q7LFL8 1/20 0.43
TET1 Q8NFU7 1/20 0.43
KDM2B Q8NHM5 1/20 0.43
CXXC4 Q9H2H0 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43
TP53 P04637 1/20 0.43
PLA2G4B P0C869 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10886888 0.96 MEN1 (0.68) KMT2ATSHRMEN1GPR119ITGB3
SCHEMBL8035917 0.92 KMT2A (0.61) KMT2ATSHRMEN1GPR119ITGB3
SCHEMBL7507062 0.91 KMT2A (0.71) KMT2ATSHRMEN1GPR119TET3
SCHEMBL7514442 0.88 KMT2A (0.55) KMT2ATSHRMEN1TET3FBXL19
SCHEMBL8043554 0.88 KMT2A (0.62) KMT2ATSHRMEN1GPR119TET3
SCHEMBL2636679 0.83 KMT2A (0.88) KMT2ATSHRMEN1TET3FBXL19
SCHEMBL7511127 0.83 MEN1 (0.48) KMT2ATSHRMEN1TP53
SCHEMBL8045479 0.83 KMT2A (0.58) KMT2ATSHRMEN1TET3FBXL19
SCHEMBL10874182 0.82 KMT2A (0.48) KMT2ATSHRMEN1TET3FBXL19
SCHEMBL4827223 0.81 MEN1 (0.47) KMT2ATSHRMEN1ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4400059-A Liquid crystal display device HITACHI, LTD. (JP) 1983-08-23 US claimed
EP-0742275-B1 LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORP (JP) 2002-03-20 EP disclosed
EP-0805134-B1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORP (JP) 2000-08-30 EP disclosed
US-5833879-A LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES CHISSO CORPORATION (JP) 1998-11-10 US disclosed
US-5779936-A FLUORINATED BICYCLOHEXANE OR CYCLOHEXYLETHYL CYCLOHEXANE DERIVATIVE HAVING LOW VISCOSITY AND HIGH CLEARING POINT TEMPERATURE CHISSO CORPORATION (JP) 1998-07-14 US disclosed
US-5720899-A Liquid crystalline compound, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1998-02-24 US disclosed
EP-0805134-A1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-11-05 EP disclosed
EP-0742275-A1 LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORPORATION (JP) 1996-11-13 EP disclosed
US-4400059-A Liquid crystal display device HITACHI, LTD. (JP) 1983-08-23 US disclosed