Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.88 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.88 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.88 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | FABP3 | P05413 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.59 |
| ▸ | PTAFR | P25105 | 1/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033464 | 1.00 | SMN1; SMN2 (0.88) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 | |
| SCHEMBL7513216 | 1.00 | SMN1; SMN2 (0.88) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 | |
| SCHEMBL2030912 | 1.00 | SMN1; SMN2 (0.88) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 | |
| SCHEMBL31294943 | 0.94 | SMN1; SMN2 (0.92) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 | |
| SCHEMBL31294950 | 0.94 | SMN1; SMN2 (0.92) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 | |
| SCHEMBL31294994 | 0.94 | SMN1; SMN2 (0.92) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 | |
| SCHEMBL31294976 | 0.94 | SMN1; SMN2 (0.92) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 | |
| SCHEMBL31294982 | 0.94 | SMN1; SMN2 (0.92) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 | |
| SCHEMBL31294958 | 0.94 | SMN1; SMN2 (0.92) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 | |
| SCHEMBL31295038 | 0.94 | SMN1; SMN2 (0.92) | SMN1; SMN2NR5A2NR5A1MAPTFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730860-B1 | Mixed micelles | HOFFMANN LA ROCHE (CH) | 2002-01-02 | — | — | EP | claimed |
| US-5747066-A | PHOSPHATIDES, BILE ACID SALT OR DIHEXANOYLLECITHIN | HOFFMANN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | claimed |
| EP-0730860-A2 | Mixed micelles | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-11 | — | — | EP | claimed |
| EP-0730860-B1 | Mixed micelles | HOFFMANN LA ROCHE (CH) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001044194-A2 | PROPANOIC ACID DERIVATIVES AS INTEGRIN INHIBITORS | CELLTECH R & D LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |
| US-5747066-A | PHOSPHATIDES, BILE ACID SALT OR DIHEXANOYLLECITHIN | HOFFMANN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |
| EP-0730860-A2 | Mixed micelles | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-11 | — | — | EP | disclosed |