Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.55 |
| ▸ | CCR7 | P32248 | 6/20 | 0.44 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512270 | 1.00 | CXCR2 (0.55) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3850785 | 0.85 | CXCR2 (0.57) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3851666 | 0.82 | CXCR2 (0.75) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3851663 | 0.82 | CXCR2 (0.75) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3851948 | 0.82 | CXCR2 (0.64) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3851505 | 0.81 | CXCR2 (0.71) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3861386 | 0.79 | CXCR2 (0.69) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3850796 | 0.79 | CXCR2 (0.68) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3851875 | 0.79 | CXCR2 (0.68) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3851449 | 0.77 | CXCR2 (0.73) | CXCR2CCR7CX3CR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259512-A1 | PTERIDINE COMPOUNDS FOR THE TREATMENT OF PSORIASIS | AstraZeneca AB (SE) | 2002-11-27 | — | — | EP | claimed |
| WO-2001062758-A1 | PTERIDINE COMPOUNDS FOR THE TREATMENT OF PSORIASIS | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | claimed |