SCHEMBL7512684

SCHEMBL7512684

C=CCOC(=O)C(=O)OCC=C.[NaH]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
TSHR P16473 4/20 0.43
MAPT P10636 4/20 0.43
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NPSR1 Q6W5P4 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPK1 P28482 1/20 0.36
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SNCA P37840 1/20 0.35
APP P05067 1/20 0.35
PTP4A3 O75365 1/20 0.35
PTP4A1 Q93096 1/20 0.35
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177943 0.97 CYP3A4 (0.48) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL21980975 0.86 CYP3A4 (0.45) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL10966895 0.86 CYP3A4 (0.45) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL6419938 0.85 CYP3A4 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL3962674 0.85 MAPT (0.42) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL999287 0.85 CYP3A4 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL669729 0.83
SCHEMBL8409550 0.83 CYP3A4 (0.43) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL28184999 0.83 TSHR (0.48) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL7038250 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020084438-A1 Liquid-absorbent resin is a crosslinked polymer obtained by polymerizing a monomer component comprising a major proportion of a cyclic N-vinyllactam NIPPON SHOKUBAI CO., LTD. (JP) 2002-07-04 US disclosed
US-6103425-A A CYCLIC N-VINYLLACTAM POLYMER IN SOLVENT POSSESSING SUPER RETAINING AN ORGANIC SOLVENT CONTAINING AN ELECTROLYTE NIPPON SHOKUBAI CO., LTD. (JP) 2000-08-15 US disclosed
EP-0846493-A1 LIQUID-ABSORBING RESIN, PROCESS FOR THE PREPARATION THEREOF, AND GEL COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 1998-06-10 EP disclosed