SCHEMBL7512809

SCHEMBL7512809

COCCOCCOc1ccc(CC(O)C(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACACB O00763 3/20 0.50
PPARG P37231 13/20 0.47
PPARD Q03181 11/20 0.47
PPARA Q07869 9/20 0.47
LDHA P00338 1/20 0.46
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CHEK1 O14757 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8953657 1.00 ACACB (0.50) ACACBPPARGPPARDPPARALDHA
SCHEMBL7511135 0.96 ACACB (0.53) ACACBPPARGPPARDPPARALDHA
SCHEMBL7506846 0.96 ACACB (0.53) ACACBPPARGPPARDPPARALDHA
SCHEMBL27128392 0.89 ACACB (0.54) ACACBPPARGPPARDPPARAITGB3
SCHEMBL27028895 0.89 ACACB (0.54) ACACBPPARGPPARDPPARAITGB3
SCHEMBL27029038 0.89 ACACB (0.54) ACACBPPARGPPARDPPARAITGB3
SCHEMBL27028997 0.89 ACACB (0.54) ACACBPPARGPPARDPPARAITGB3
SCHEMBL27128110 0.89 ACACB (0.54) ACACBPPARGPPARDPPARAITGB3
SCHEMBL27028999 0.89 ACACB (0.54) ACACBPPARGPPARDPPARAITGB3
SCHEMBL27654994 0.88 PPARG (0.54) PPARGPPARDPPARALDHAITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0634408-B1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO (JP) 2002-01-02 EP disclosed
EP-0634408-A1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-01-18 EP disclosed