Fructose

Fructose

SCHEMBL751281

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nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.54
TSHR P16473 1/20 0.54
PDE4A P27815 1/20 0.54
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
USP2 O75604 1/20 0.45
SLCO1B1 Q9Y6L6 1/20 0.45
KDM4E B2RXH2 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fructose SCHEMBL8469522 1.00 CYP2C9 (0.54) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL80090 0.98 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL9711052 0.98 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL7549336 0.98 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL19744235 0.98 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL159418 0.98 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Tagatose SCHEMBL16196803 0.98 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL1054095 0.98 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Fructose SCHEMBL7707744 0.98 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1
Tagatose SCHEMBL7524214 0.98 CYP2C9 (0.56) CYP2C9TSHRPDE4ALMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190083452-A1 THERAPEUTIC AGENTS CONTAINING CANNABIS FLAVONOID DERIVATIVES FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS LOTHERA, LLC 2019-03-21 US claimed
EP-2429586-A1 ORALLY DISINTEGRATING EXCIPIENT Jrs Pharma GmbH+Co.kG (DE) 2012-03-21 EP disclosed
WO-2010132431-A1 ORALLY DISINTEGRATING EXCIPIENT JRS PHARMA GMBH+CO.KG (DE) 2010-11-18 WO disclosed
EP-0973507-A4 DOSAGE FORM EXHIBITING RAPID DISPERSE PROPERTIES, METHODS OF USE AND PROCESS FOR THE MANUFACTURE OF SAME THERICS INC (US) 2006-08-23 EP disclosed
EP-1139773-A4 CONTROLLING RELEASE OF ACTIVE AGENTS FROM A CHEWING GUM COATING WRIGLEY W M JUN CO (US) 2002-06-12 EP disclosed
EP-1139773-A1 CONTROLLING RELEASE OF ACTIVE AGENTS FROM A CHEWING GUM COATING WM. WRIGLEY JR. COMPANY (US) 2001-10-10 EP disclosed
WO-2000035295-A1 CONTROLLING RELEASE OF ACTIVE AGENTS FROM A CHEWING GUM COATING WM. WRIGLEY JR. COMPANY (US) 2000-06-22 WO disclosed
EP-0973507-A1 DOSAGE FORM EXHIBITING RAPID DISPERSE PROPERTIES, METHODS OF USE AND PROCESS FOR THE MANUFACTURE OF SAME Therics, Inc. (US) 2000-01-26 EP disclosed
WO-1998036738-A1 DOSAGE FORM EXHIBITING RAPID DISPERSE PROPERTIES, METHODS OF USE AND PROCESS FOR THE MANUFACTURE OF SAME THERICS, INC. (US) 1998-08-27 WO disclosed
US-5380541-A Sucralose compositions TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1995-01-10 US disclosed
WO-1989003182-A1 SUCRALOSE COMPOSITIONS TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1989-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190083452-A1 THERAPEUTIC AGENTS CONTAINING CANNABIS FLAVONOID DERIVATIVES FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS NCSTN, CHLSN, CNTN1 CYP2C9 2686/4885TSHR 4864/4885PDE4A 3822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.