Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 11/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570670 | 0.84 | FFAR1 (0.71) | HRH3FFAR1PPARACYP3A4MAPT | |
| SCHEMBL9570653 | 0.83 | FFAR1 (0.69) | HRH3FFAR1PPARACYP3A4MAPT | |
| SCHEMBL9570574 | 0.83 | FFAR1 (0.69) | HRH3FFAR1PPARACYP3A4MAPT | |
| SCHEMBL9570566 | 0.83 | FFAR1 (0.69) | HRH3FFAR1PPARACYP3A4MAPT | |
| SCHEMBL9570697 | 0.83 | FFAR1 (0.69) | HRH3FFAR1PPARACYP3A4MAPT | |
| SCHEMBL8957444 | 0.83 | FFAR1 (0.69) | HRH3FFAR1PPARACYP3A4MAPT | |
| SCHEMBL9570560 | 0.83 | FFAR1 (0.69) | HRH3FFAR1PPARACYP3A4MAPT | |
| SCHEMBL9570853 | 0.83 | FFAR1 (0.69) | HRH3FFAR1PPARACYP3A4MAPT | |
| SCHEMBL9570659 | 0.83 | FFAR1 (0.69) | HRH3FFAR1PPARACYP3A4MAPT | |
| SCHEMBL1299561 | 0.82 | HRH3 (0.63) | HRH3FFAR1PPARACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022274-B1 | Intermediates for the preparation of Oxazolidinedione and Thiazolidinedione derivatves | SANKYO CO (JP) | 2002-08-28 | — | — | EP | disclosed |
| EP-0676398-B1 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6117893-A | Heterocyclic compounds having anti-diabetic activity and their use | SANKYO COMPANY, LIMITED (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-1022274-A1 | Oxazolidinedione and Thiazolidinedione derivatves, their preparation and their use | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5977365-A | HYPOGLYCEMIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |