SCHEMBL7513129

SCHEMBL7513129

COCCN(C)C(=O)c1cn(C(CC2CCN(C(=O)OCc3ccc(F)cc3)CC2)c2cnc[nH]2)cc1-c1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FNTA P49354 9/20 0.42
FNTB P49356 9/20 0.42
PGGT1B P53609 1/20 0.42
GRIN2B Q13224 3/20 0.35
ENPP2 Q13822 6/20 0.35
KCNH2 Q12809 2/20 0.35
HTR2C P28335 1/20 0.34
TRPC3 Q13507 1/20 0.32
TRPC7 Q9HCX4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7504941 0.95 FNTA (0.42) FNTAFNTBPGGT1BGRIN2BENPP2
SCHEMBL7504480 0.93 FNTA (0.43) FNTAFNTBPGGT1BENPP2KCNH2
SCHEMBL7508810 0.92 FNTA (0.42) FNTAFNTBPGGT1BENPP2KCNH2
SCHEMBL7508235 0.90 FNTA (0.43) FNTAFNTBPGGT1BHTR2C
SCHEMBL7508735 0.90 FNTA (0.42) FNTAFNTBPGGT1BHTR2C
SCHEMBL7508123 0.89 FNTA (0.42) FNTAFNTBPGGT1BHTR2C
SCHEMBL7503289 0.88 FNTA (0.44) FNTAFNTBPGGT1BHTR2C
SCHEMBL7508599 0.87 FNTA (0.38) FNTAFNTBPGGT1BENPP2KCNH2
SCHEMBL7508968 0.87 FNTA (0.43) FNTAFNTBPGGT1BHTR2C
SCHEMBL7504158 0.87 FNTA (0.39) FNTAFNTBPGGT1BHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1058683-B1 FARNESYL TRANSFERASE INHIBITORS HAVING A PIPERIDINE STRUCTURE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LTD (KR) 2002-12-04 EP claimed