Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 17/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506537 | 0.89 | LCK (0.54) | LCKMKNK1MKNK2 | |
| SCHEMBL7505858 | 0.89 | LCK (0.55) | LCKMKNK1MKNK2 | |
| SCHEMBL7514593 | 0.88 | LCK (0.54) | LCKMKNK1MKNK2 | |
| SCHEMBL7502279 | 0.87 | LCK (0.57) | LCKMKNK1MKNK2 | |
| SCHEMBL7507450 | 0.86 | LCK (0.69) | LCKMKNK1MKNK2 | |
| SCHEMBL7588289 | 0.85 | LCK (0.75) | LCK | |
| SCHEMBL7505773 | 0.81 | LCK (0.63) | LCKMKNK1MKNK2 | |
| SCHEMBL7514449 | 0.81 | LCK (0.61) | LCKMKNK1MKNK2 | |
| SCHEMBL7506201 | 0.81 | LCK (0.58) | LCKMKNK1MKNK2 | |
| SCHEMBL7577238 | 0.80 | LCK (0.66) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206260-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1206260-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000207-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |