⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355540 | 0.81 | UHRF1 (0.54) | — | |
| SCHEMBL212981 | 0.79 | — | — | |
| SCHEMBL29371239 | 0.79 | — | — | |
| SCHEMBL363433 | 0.78 | UHRF1 (0.46) | — | |
| SCHEMBL10676593 | 0.77 | — | — | |
| SCHEMBL14546332 | 0.77 | — | — | |
| SCHEMBL510339 | 0.77 | — | — | |
| SCHEMBL5083679 | 0.77 | — | — | |
| SCHEMBL15132893 | 0.77 | — | — | |
| SCHEMBL1980498 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439174-B1 | 4-IMIDAZOLIN-2-ONE COMPOUNDS AS p38 MAP KINASE INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |