Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7378358 | 0.85 | F10 (0.34) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7544782 | 0.75 | F10 (0.36) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7377600 | 0.75 | F10 (0.36) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1652937 | 0.70 | F10 (0.58) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1652938 | 0.70 | F10 (0.58) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7379160 | 0.69 | F10 (0.38) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7518291 | 0.69 | F10 (0.38) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7537562 | 0.67 | F10 (0.56) | F10F2KLKB1 | |
| SCHEMBL7537104 | 0.65 | F10 (0.36) | F10CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1651500 | 0.65 | F10 (0.40) | F10CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086099-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1086099-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | Aventis Pharmaceuticals Products Inc. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999062904-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-12-09 | — | — | WO | disclosed |