Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522623 | 0.90 | CYP1A2 (0.32) | KCNH2 | |
| SCHEMBL4525375 | 0.89 | TOP1 (0.31) | KCNH2 | |
| SCHEMBL7512498 | 0.88 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL1382901 | 0.88 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL1384915 | 0.84 | KCNH2 (0.30) | KCNH2 | |
| SCHEMBL7509686 | 0.84 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL1381764 | 0.82 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL4510736 | 0.81 | — | — | |
| SCHEMBL4511107 | 0.78 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL1384224 | 0.78 | KCNH2 (0.34) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |