⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155313 | 0.78 | — | — | |
| SCHEMBL28067799 | 0.71 | — | — | |
| SCHEMBL2786027 | 0.71 | — | — | |
| SCHEMBL15145725 | 0.71 | — | — | |
| SCHEMBL3801803 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL28108026 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL27744922 | 0.70 | — | — | |
| SCHEMBL5393991 | 0.68 | — | — | |
| SCHEMBL28601965 | 0.68 | — | — | |
| SCHEMBL1136783 | 0.68 | CYP17A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101955552-B | Monosubstituted alkyl bond-connected amino and imidazolyl double-front point centre beta-cyclodextrin and preparation method thereof | UNIV NANJING SCIENCE & TECH | 2013-01-23 | — | — | CN | claimed |
| CN-101955552-A | Monosubstituted alkyl bond-connected amino and imidazolyl double-front point centre beta-cyclodextrin and preparation method thereof | UNIV NANJING SCIENCE & TECH | 2011-01-26 | — | — | CN | claimed |
| EP-1105412-A1 | SERINE PROTEASE INHIBITORS COMPRISING ALPHA-KETO HETEROCYCLES | CORTECH, INC. (US) | 2001-06-13 | — | — | EP | claimed |
| US-6159938-A | Serine protease inhibitors comprising α-keto heterocycles | CORTECH, INC. | 2000-12-12 | — | — | US | claimed |
| WO-2000009542-A1 | SERINE PROTEASE INHIBITORS COMPRISING α-KETO HETEROCYCLES | CORTECH, INC. (US) | 2000-02-24 | — | — | WO | claimed |
| CN-101955552-B | Monosubstituted alkyl bond-connected amino and imidazolyl double-front point centre beta-cyclodextrin and preparation method thereof | UNIV NANJING SCIENCE & TECH | 2013-01-23 | — | — | CN | disclosed |
| CN-101955552-A | Monosubstituted alkyl bond-connected amino and imidazolyl double-front point centre beta-cyclodextrin and preparation method thereof | UNIV NANJING SCIENCE & TECH | 2011-01-26 | — | — | CN | disclosed |
| EP-0956379-B1 | USE OF 1-AMIDOALKYLIMIDAZOLES FOR INHIBITING CORROSION | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-1105412-A1 | SERINE PROTEASE INHIBITORS COMPRISING ALPHA-KETO HETEROCYCLES | CORTECH, INC. (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6159938-A | Serine protease inhibitors comprising α-keto heterocycles | CORTECH, INC. | 2000-12-12 | — | — | US | disclosed |
| US-6077460-A | 1-AMIDOALKYLIMIDAZOLES. | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-20 | — | — | US | disclosed |
| WO-2000009542-A1 | SERINE PROTEASE INHIBITORS COMPRISING α-KETO HETEROCYCLES | CORTECH, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| EP-0956379-A2 | CORROSION INHIBITION | BASF Aktiengesellschaft (DE) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998002415-A2 | METHOD FOR INHIBITING CORROSION AND PROCESS FOR PREPARING 1-AMIDOALKYLIMIDAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-22 | — | — | WO | disclosed |
| US-4791229-A | WITH ACETIC ACID SOLVENT AND AUXILIARY BASE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-13 | — | — | US | disclosed |
| US-4514413-A | ANTACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1985-04-30 | — | — | US | disclosed |