Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515861 | 1.00 | MEN1 (0.40) | MEN1KMT2AARKCNH2SRD5A1 | |
| SCHEMBL11329447 | 0.89 | AR (0.42) | MEN1KMT2AARSRD5A1CYP3A4 | |
| SCHEMBL11329429 | 0.89 | AR (0.42) | MEN1KMT2AARSRD5A1CYP3A4 | |
| SCHEMBL23378235 | 0.85 | AR (0.44) | MEN1KMT2AARSRD5A1CYP3A4 | |
| SCHEMBL27369411 | 0.85 | AR (0.42) | MEN1KMT2AARSRD5A1CYP3A4 | |
| SCHEMBL7196166 | 0.83 | AR (0.44) | ARKCNH2SRD5A1CYP3A4NR3C1 | |
| SCHEMBL17808699 | 0.83 | CYP3A4 (0.42) | MEN1KMT2AARKCNH2SRD5A1 | |
| SCHEMBL7196165 | 0.83 | AR (0.44) | ARKCNH2SRD5A1CYP3A4NR3C1 | |
| SCHEMBL23378067 | 0.83 | SRD5A1 (0.41) | MEN1KMT2AARSRD5A1 | |
| SCHEMBL6443645 | 0.83 | MEN1 (0.46) | MEN1KMT2AARSRD5A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020183532-A1 | Bioavailable prodrugs of androgenic steroids and related method | BIOTEST LABORATORIES, LLC | 2002-12-05 | — | — | US | claimed |