Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803002 | 0.84 | ADRB3 (0.65) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6797304 | 0.79 | ADRB3 (0.67) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6797300 | 0.79 | ADRB3 (0.67) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6074794 | 0.79 | ADRB3 (0.60) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6074581 | 0.78 | ADRB3 (0.76) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6074579 | 0.78 | ADRB3 (0.76) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6074831 | 0.78 | ADRB3 (0.59) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6075384 | 0.78 | ADRB3 (0.59) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6074777 | 0.77 | ADRB3 (0.58) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6802531 | 0.77 | ADRB3 (0.61) | ADRB3ADRB2ADRB1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006274-A1 | N-(4-SULFONYLARYL)CYCLYLAMINE-2-HYDROXYETHYLAMINES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |