Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 18/20 | 0.77 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.38 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516050 | 1.00 | P2RY12 (0.77) | P2RY12NAE1UBA3 | |
| SCHEMBL7510387 | 0.94 | P2RY12 (0.77) | P2RY12 | |
| SCHEMBL7510382 | 0.94 | P2RY12 (0.77) | P2RY12 | |
| SCHEMBL7505466 | 0.93 | P2RY12 (0.73) | P2RY12NAE1UBA3 | |
| SCHEMBL7505471 | 0.93 | P2RY12 (0.73) | P2RY12NAE1UBA3 | |
| SCHEMBL7509891 | 0.91 | P2RY12 (0.70) | P2RY12 | |
| SCHEMBL7509882 | 0.91 | P2RY12 (0.70) | P2RY12 | |
| SCHEMBL7508795 | 0.89 | P2RY12 (0.70) | P2RY12NAE1UBA3 | |
| SCHEMBL7508792 | 0.89 | P2RY12 (0.70) | P2RY12NAE1UBA3 | |
| SCHEMBL6995281 | 0.87 | P2RY12 (1.00) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946561-B1 | TRIAZOLO(4,5-D)PYRIMIDINYL DERIVATIVES AND THEIR USE AS MEDICAMENTS | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | claimed |
| US-6297232-B1 | TREATMENT OF PLATELET AGGREGATION DISORDERS. | ASTRAZENECA AB (SE) | 2001-10-02 | — | — | US | claimed |
| EP-0946561-B1 | TRIAZOLO(4,5-D)PYRIMIDINYL DERIVATIVES AND THEIR USE AS MEDICAMENTS | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| US-6297232-B1 | TREATMENT OF PLATELET AGGREGATION DISORDERS. | ASTRAZENECA AB (SE) | 2001-10-02 | — | — | US | disclosed |