SCHEMBL7516082

SCHEMBL7516082

O=C(O)[C@H](O)Cc1ccc2c(c1)OCO2

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.62
CYP2D6 P10635 2/20 0.59
SLC6A4 P31645 3/20 0.58
ALDH1A1 P00352 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C19 P33261 1/20 0.58
TAAR1 Q96RJ0 3/20 0.55
SLC6A2 P23975 2/20 0.55
SLC6A3 Q01959 2/20 0.55
KDM6B O15054 1/20 0.54
NPSR1 Q6W5P4 1/20 0.51
LMNA P02545 1/20 0.50
NPC1 O15118 1/20 0.49
HPGD P15428 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30052034 1.00 CYP3A4 (0.62) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2
SCHEMBL2457093 1.00 CYP3A4 (0.62) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2
SCHEMBL8953616 1.00 CYP3A4 (0.62) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2
SCHEMBL3350938 0.90 KDM6B (0.54) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2
SCHEMBL3359174 0.90 KDM6B (0.54) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2
SCHEMBL3350932 0.90 KDM6B (0.54) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2
SCHEMBL7307051 0.87 CYP3A4 (0.63) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2
SCHEMBL19369643 0.86 CYP3A4 (0.60) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2
SCHEMBL4329251 0.85 CYP3A4 (0.61) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2
SCHEMBL14377906 0.85 CYP3A4 (0.61) CYP3A4CYP2D6SLC6A4ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103833546-B The method of asymmetric synthesis of optical purity danshensu and its derivatives XI'AN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2015-12-02 CN disclosed
CN-103833546-A Asymmetric synthesis method of optically pure tanshinol and derivative of tanshinol UNIV XI AN SCI & TECHNOLOGY 2014-06-04 CN disclosed
EP-0634408-B1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO (JP) 2002-01-02 EP disclosed
US-5514773-A PARASITICIDES, ANTHELMINTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-05-07 US disclosed
EP-0634408-A1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-01-18 EP disclosed