⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11351892 | 0.78 | — | — | |
| SCHEMBL537522 | 0.73 | — | — | |
| SCHEMBL24712634 | 0.70 | — | — | |
| SCHEMBL22931665 | 0.70 | — | — | |
| SCHEMBL1315447 | 0.70 | — | — | |
| 2,2,3-Trimethylbutane SCHEMBL1788862 | 0.67 | — | — | |
| SCHEMBL5525403 | 0.67 | — | — | |
| 2,2,3-Trimethylbutane SCHEMBL11400965 | 0.67 | — | — | |
| SCHEMBL22167055 | 0.67 | — | — | |
| SCHEMBL15056336 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114642735-A | Methods, compositions and systems for delivering therapeutic and diagnostic agents into cells | 菲泽尔克斯公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-107530436-B | Methods, compositions and systems for delivering therapeutic and diagnostic agents into cells | 菲泽尔克斯公司 | 2022-03-29 | — | — | CN | disclosed |
| WO-2001007013-A9 | THIOAMIDE MOIETY-CONTAINING POLYMER DRUG CONJUGATES | UNIV NEW JERSEY MED (US) | 2002-11-14 | — | — | WO | disclosed |
| US-6468522-B1 | Controlled release of thioamide moiety-containing therapeutic agents | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2002-10-22 | — | — | US | disclosed |
| US-20020122785-A1 | Materials and processes for controlled release of thioamide moiety-containing therapeutic agents by linking to thiol-containing polymers | STEIN STANLEY (US) | 2002-09-05 | — | — | US | disclosed |
| WO-2001007013-A2 | THIOAMIDE MOIETY-CONTAINING POLYMER DRUG CONJUGATES | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2001-02-01 | — | — | WO | disclosed |