⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517377 | 1.00 | — | — | |
| SCHEMBL7524700 | 1.00 | — | — | |
| SCHEMBL7516187 | 1.00 | — | — | |
| SCHEMBL7516180 | 1.00 | — | — | |
| SCHEMBL7523825 | 0.78 | — | — | |
| SCHEMBL7521216 | 0.78 | — | — | |
| SCHEMBL7518840 | 0.78 | — | — | |
| SCHEMBL7519454 | 0.78 | — | — | |
| SCHEMBL7518834 | 0.78 | — | — | |
| SCHEMBL7519410 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032655-B | EGFR and/or HER2 inhibitors and methods of use | 达纳-法伯癌症研究所股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-111032655-A | EGFR and/or HER2 inhibitors and methods of use | 达纳-法伯癌症研究所股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-1107666-C | Synthesis process of alpha, alpha-dihalogen pentaneldial, dihalogen acid and their derivative | GUANGZHOU INST OF CHEMISTRY (CN) | 2003-05-07 | — | — | CN | disclosed |
| US-20020042055-A1 | Alteration of hydrolase genes and screening of the resulting libraries for the ability to catalyze specific reactions | MAXYGEN, INC. | 2002-04-11 | — | — | US | disclosed |
| WO-2001046476-A1 | ALTERATION OF HYDROLASE GENES AND SCREENING OF THE RESULTING LIBRARIES FOR THE ABILITY TO CATALYZE SPECIFIC REACTIONS | MAXYGEN, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| CN-1277178-A | Synthesis process of alpha, alpha-dihalogen pentaneldial, dihalogen acid and their derivative | GUANGZHOU INST OF CHEMISTRY AC (CN) | 2000-12-20 | — | — | CN | disclosed |