Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP11A1 | P05108 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847668 | 0.89 | CYP19A1 (0.54) | CYP19A1CRBNDDB1 | |
| SCHEMBL11851739 | 0.78 | CYP19A1 (0.55) | CYP19A1CRBNDDB1CYP3A4CYP17A1 | |
| SCHEMBL11843650 | 0.75 | CYP19A1 (0.51) | CYP19A1CRBNDDB1 | |
| SCHEMBL9472649 | 0.73 | CYP19A1 (0.49) | CYP19A1CRBNDDB1CYP3A4CYP17A1 | |
| SCHEMBL6139183 | 0.71 | CYP19A1 (0.47) | CYP19A1 | |
| SCHEMBL11098333 | 0.71 | MEN1 (0.47) | — | |
| SCHEMBL9735641 | 0.68 | GRIN1 (0.45) | — | |
| SCHEMBL459724 | 0.67 | DDB1 (0.51) | CYP19A1CRBNDDB1CYP3A4CYP17A1 | |
| SCHEMBL27313214 | 0.67 | MEN1 (0.41) | CYP19A1CRBNDDB1CYP3A4CYP17A1 | |
| SCHEMBL19370835 | 0.67 | DDB1 (0.51) | CYP19A1CRBNDDB1CYP3A4CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452012-B1 | USEFULL CHEMICAL INTERMEDIATES FOR SYNTHESIS OF NEUROKININ ANTAGONISTS | SANOFI-SYNTHELABO (FR) | 2002-09-17 | — | — | US | disclosed |
| US-6342607-B1 | INTERMEDIATES FOR PREPARATION OF NEUROKININ ANTAGONISTS | SANOFI-SYNTHELABO (FR) | 2002-01-29 | — | — | US | disclosed |