Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526850 | 0.93 | PTPN1 (0.46) | PTPN1PTPN2KDM4E | |
| SCHEMBL7516893 | 0.89 | PTPN1 (0.50) | PTPN1PTPN2SCN4ASCN9ASCN3A | |
| SCHEMBL7519093 | 0.86 | PTPN1 (0.46) | PTPN1PTPN2KDM4EHPGDHSD17B10 | |
| SCHEMBL7521290 | 0.85 | PTPN1 (0.54) | PTPN1PTPN2 | |
| SCHEMBL7702006 | 0.85 | KDM4E (0.46) | SCN4ASCN9ASCN3AKDM4EHPGD | |
| SCHEMBL7521793 | 0.81 | PTPN1 (0.53) | PTPN1PTPN2SCN4ASCN9ASCN3A | |
| SCHEMBL7524247 | 0.81 | PTPN1 (0.53) | PTPN1PTPN2SCN4ASCN9ASCN3A | |
| SCHEMBL6318391 | 0.80 | KDM4E (0.52) | PTPN1PTPN2SCN4ASCN9ASCN3A | |
| SCHEMBL7699895 | 0.79 | KMT2A (0.42) | SCN4ASCN9ASCN3AKDM4EHPGD | |
| SCHEMBL7521067 | 0.77 | PTPN1 (0.47) | PTPN1PTPN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | claimed |
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | claimed |
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPN1, PTPRO, PTPRS | PTPN1 1/4885PTPN2 14/4885SCN4A 1872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.