Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TGM1 | P22735 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536121 | 0.78 | F13A1 (0.55) | ALDH1A1KDM4EMEN1KMT2AF13A1 | |
| SCHEMBL8858915 | 0.77 | F13A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AF13A1 | |
| SCHEMBL4681355 | 0.76 | F13A1 (0.52) | ALDH1A1KDM4EMEN1KMT2AF13A1 | |
| Hydrochloric Acid SCHEMBL4681749 | 0.75 | F13A1 (0.51) | ALDH1A1KDM4EMEN1KMT2AF13A1 | |
| SCHEMBL5536676 | 0.75 | F13A1 (0.52) | ALDH1A1KDM4EMEN1KMT2AF13A1 | |
| SCHEMBL5536669 | 0.75 | F13A1 (0.49) | ALDH1A1KDM4EMEN1KMT2AF13A1 | |
| SCHEMBL5540105 | 0.75 | F13A1 (0.52) | ALDH1A1KDM4EMEN1KMT2AF13A1 | |
| SCHEMBL5546135 | 0.74 | F13A1 (0.51) | ALDH1A1KDM4EMEN1KMT2AF13A1 | |
| SCHEMBL27610430 | 0.74 | F13A1 (0.48) | ALDH1A1KDM4EMEN1KMT2AF13A1 | |
| SCHEMBL5539625 | 0.73 | F13A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002540072-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1165082-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-06-12 | — | — | EP | claimed |
| EP-1165082-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000051611-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | claimed |