Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990473 | 1.00 | CA1 (0.47) | CA1CA2TBXAS1MEN1KMT2A | |
| SCHEMBL7507247 | 0.96 | CA1 (0.44) | CA1CA2TBXAS1MEN1KMT2A | |
| SCHEMBL7502596 | 0.87 | NR4A1 (0.49) | CA1CA2TBXAS1MEN1KMT2A | |
| SCHEMBL7989817 | 0.87 | NR4A1 (0.49) | CA1CA2TBXAS1MEN1KMT2A | |
| SCHEMBL7975459 | 0.84 | CA1 (0.43) | CA1CA2MEN1KMT2ANPC1 | |
| SCHEMBL5742123 | 0.83 | CA1 (0.56) | CA1CA2KMT2ATSHR | |
| SCHEMBL9233919 | 0.82 | TSHR (0.62) | CA1CA2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7987465 | 0.81 | CA1 (0.47) | CA1CA2KMT2ATSHR | |
| SCHEMBL7988927 | 0.81 | CA1 (0.47) | CA1CA2KMT2ATSHR | |
| SCHEMBL7989918 | 0.81 | CA1 (0.50) | CA1CA2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175385-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Pharmacor Inc. (CA) | 2002-01-30 | — | — | EP | disclosed |
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |
| WO-2000066524-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PHARMACOR INC. (CA) | 2000-11-09 | — | — | WO | disclosed |