Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516980 | 1.00 | GNRHR (0.60) | GNRHRCACNA1B | |
| SCHEMBL7514192 | 0.91 | GNRHR (0.56) | GNRHRCACNA1B | |
| SCHEMBL7514184 | 0.91 | GNRHR (0.56) | GNRHRCACNA1B | |
| SCHEMBL7855392 | 0.89 | GNRHR (0.57) | GNRHRCACNA1B | |
| SCHEMBL7855390 | 0.89 | GNRHR (0.57) | GNRHRCACNA1B | |
| SCHEMBL7980537 | 0.88 | GNRHR (0.69) | GNRHR | |
| SCHEMBL7980539 | 0.88 | GNRHR (0.69) | GNRHR | |
| SCHEMBL7863999 | 0.81 | GNRHR (0.53) | GNRHRCACNA1B | |
| SCHEMBL7863995 | 0.81 | GNRHR (0.53) | GNRHRCACNA1B | |
| SCHEMBL7512785 | 0.78 | GNRHR (0.52) | GNRHRCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049472-A4 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1049472-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999021557-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1999-05-06 | — | — | WO | disclosed |