Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.62 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517794 | 1.00 | SRD5A2 (0.62) | SRD5A2SRD5A1ARLMNACYP3A4 | |
| SCHEMBL7520659 | 0.92 | SRD5A2 (0.72) | SRD5A2SRD5A1ARLMNACYP3A4 | |
| SCHEMBL7520654 | 0.92 | SRD5A2 (0.72) | SRD5A2SRD5A1ARLMNACYP3A4 | |
| SCHEMBL7521406 | 0.91 | SRD5A2 (0.62) | SRD5A2SRD5A1ARLMNACYP3A4 | |
| SCHEMBL7521398 | 0.91 | SRD5A2 (0.62) | SRD5A2SRD5A1ARLMNACYP3A4 | |
| SCHEMBL7520592 | 0.84 | SRD5A1 (0.86) | SRD5A2SRD5A1LMNACYP3A4CYP2C9 | |
| SCHEMBL7520589 | 0.84 | SRD5A1 (0.86) | SRD5A2SRD5A1LMNACYP3A4CYP2C9 | |
| SCHEMBL7524913 | 0.83 | SRD5A2 (0.72) | SRD5A2SRD5A1AR | |
| SCHEMBL7524919 | 0.83 | SRD5A2 (0.72) | SRD5A2SRD5A1AR | |
| SCHEMBL5699657 | 0.82 | SRD5A2 (0.68) | SRD5A2SRD5A1ARLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970105-B1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN SPA (IT) | 2002-02-27 | — | — | EP | claimed |
| EP-0970105-A1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-12 | — | — | EP | claimed |
| WO-1999035161-A1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN SPA (IT) | 1999-07-15 | — | — | WO | claimed |
| EP-0970105-B1 | PROCESS FOR PREPARING CARBOXAMIDO-4-AZASTEROIDS | PHARMACIA & UPJOHN SPA (IT) | 2002-02-27 | — | — | EP | disclosed |
| US-6284887-B1 | PREPARING 17.BETA.-CARBOXAMIDO-4-AZASTEROIDS STARTING FROM THE CORRESPONDING 17.BETA.-CARBONYLIMIDAZOLE DERIVATIVES. | PHARMACIA & UPJOHN SPA (IT) | 2001-09-04 | — | — | US | disclosed |
| US-6121449-A | Process for preparing carboxamido-4-azasteroids | PHARMACIA & UPJOHN SPA (IT) | 2000-09-19 | — | — | US | disclosed |