Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HINT1 | P49773 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279179 | 1.00 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL16609224 | 0.92 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL6470562 | 0.89 | KDM4E (0.62) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL17279165 | 0.89 | KDM4E (0.62) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL8665070 | 0.89 | KDM4E (0.62) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL16609168 | 0.87 | KDM4E (0.52) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL19662703 | 0.85 | KDM4E (0.61) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL18671304 | 0.85 | KDM4E (0.61) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL3821420 | 0.85 | KDM4E (0.61) | KDM4ETAS1R3TAS1R1TYMPPOLA1 | |
| SCHEMBL3821424 | 0.85 | KDM4E (0.61) | KDM4ETAS1R3TAS1R1TYMPPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882059-B1 | SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3-'P5'- PHOSPHORAMIDATES | LYNX THERAPEUTICS INC (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-0882059-A1 | SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3-'P5'- PHOSPHORAMIDATES | LYNX THERAPEUTICS, INC. (US) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997031009-A1 | SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3'→P5' PHOSPHORAMIDATES | LYNX THERAPEUTICS, INC. (US) | 1997-08-28 | — | — | WO | disclosed |