Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.53 |
| ▸ | PPARG | P37231 | 15/20 | 0.53 |
| ▸ | PPARD | Q03181 | 11/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752341 | 0.89 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6748817 | 0.89 | PPARG (0.57) | PPARAPPARGPPARDPTGDR2 | |
| SCHEMBL6752656 | 0.88 | PPARG (0.58) | PPARAPPARGPPARDPTGDR2 | |
| SCHEMBL6752358 | 0.87 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL6752520 | 0.86 | PPARA (0.51) | PPARAPPARGPPARDPTPN1 | |
| SCHEMBL6748845 | 0.84 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL6754497 | 0.84 | PPARG (0.47) | PPARAPPARGPPARDPTGDR2 | |
| SCHEMBL6752330 | 0.78 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL6754496 | 0.78 | PPARA (0.62) | PPARAPPARGPPARD | |
| SCHEMBL6752674 | 0.78 | PPARA (0.65) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020065268-A1 | New compounds, their preparation and use | JEPPESEN LONE (DK) | 2002-05-30 | — | — | US | claimed |
| EP-1123297-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-08-16 | — | — | EP | claimed |
| WO-2000023451-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-04-27 | — | — | WO | claimed |
| US-20020065267-A1 | Compounds, their preparation and use | JEPPESEN LONE (DK) | 2002-05-30 | — | — | US | disclosed |
| US-20020061880-A1 | New compounds, their preparation and use | JEPPESEN LONE (DK) | 2002-05-23 | — | — | US | disclosed |
| US-20020061876-A1 | Compounds, their preparation and use | JEPPESEN LONE (DK) | 2002-05-23 | — | — | US | disclosed |
| EP-1179435-A1 | Reversible thermochromic composition having improved light-fastness and product comprising same | The Pilot Ink Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061880-A1 | New compounds, their preparation and use | PPARG, PPARD, PPARA | PPARA 3/4885PPARG 1/4885PPARD 2/4885 |
| US-20020065267-A1 | Compounds, their preparation and use | PPARG, PPARA, PPARD | PPARA 2/4885PPARG 1/4885PPARD 3/4885 |
| US-20020061876-A1 | Compounds, their preparation and use | PPARG, PPARA, PPARD | PPARA 2/4885PPARG 1/4885PPARD 3/4885 |
| US-20020065268-A1 | New compounds, their preparation and use | PPARG, PPARD, PPARA | PPARA 3/4885PPARG 1/4885PPARD 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.