SCHEMBL751818

SCHEMBL751818

O=C(CC(=O)C(F)(F)F)c1cc(Br)cs1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 3/20 0.56
ALDH1A1 P00352 3/20 0.51
LMNA P02545 2/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.43
PLOD2 O00469 3/20 0.42
PLOD3 O60568 2/20 0.41
PLOD1 Q02809 2/20 0.41
HDAC6 Q9UBN7 3/20 0.35
MAPT P10636 2/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ERCC5 P28715 1/20 0.34
FEN1 P39748 1/20 0.34
ALAD P13716 1/20 0.33
HDAC4 P56524 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23617480 0.77 GSK3B (0.61) GSK3BALDH1A1LMNACES2CES1
SCHEMBL21651048 0.76 MAPT (0.39) GSK3BCES1PLOD2PLOD3PLOD1
SCHEMBL756674 0.76 MEN1 (0.36) GSK3BALDH1A1SMN1; SMN2PLOD2PLOD3
SCHEMBL2224044 0.76 CES1 (0.59) GSK3BALDH1A1LMNACES2CES1
SCHEMBL15988671 0.75 GSK3B (0.70) GSK3BALDH1A1LMNACES2CES1
SCHEMBL23330432 0.74 GSK3B (0.58) GSK3BALDH1A1LMNACES2CES1
SCHEMBL15282434 0.74 GSK3B (0.68) GSK3BALDH1A1LMNACES2CES1
SCHEMBL347869 0.72 GSK3B (0.58) GSK3BALDH1A1LMNACES2CES1
SCHEMBL553084 0.72 GSK3B (0.66) GSK3BALDH1A1LMNACES2CES1
SCHEMBL6784161 0.72 GSK3B (1.00) GSK3BALDH1A1LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1245659-B2 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2020-03-11 EP disclosed
US-10141513-B2 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-11-27 US disclosed
US-20140183508-A1 POLYMERIC LIGHT EMITTING SUBSTANCE AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-03 US disclosed
EP-2258805-B1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2013-10-30 EP disclosed
EP-2258809-B1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2013-06-19 EP disclosed
EP-2258808-B1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2013-04-24 EP disclosed
EP-2258806-B1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2013-04-24 EP disclosed
EP-1245659-B9 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2012-07-04 EP disclosed
EP-1245659-B1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL CO (JP) 2012-03-21 EP disclosed
US-20110187969-A1 POLYMERIC LIGHT EMITTING SUBSTANCE AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-04 US disclosed
US-7947340-B2 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-24 US disclosed
EP-2258805-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
EP-2258806-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
EP-2258808-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
EP-2258809-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
EP-2258807-A2 Polymeric light emitting substance and polymer light emitting device using the same Sumitomo Chemical Company, Limited (JP) 2010-12-08 EP disclosed
US-20020193532-A1 Comprises polystyrene and organometallic polymer; luminescence; for use in spin coating and ink jet printing SUMITOMO CHEMICAL COMPANY, LIMITED 2002-12-19 US disclosed
EP-1245659-A1 Polymeric light emitting substance and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-02 EP disclosed