Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL6131252 | 0.95 | TSHR (0.46) | TSHRALDH1A1HCAR2ADRA1APDE4D | |
| SCHEMBL21772350 | 0.93 | TSHR (0.52) | TSHRALDH1A1HCAR2ADRA1APDE4D | |
| SCHEMBL15253 | 0.93 | — | — | |
| Benzene SCHEMBL27682798 | 0.91 | TSHR (0.46) | TSHRALDH1A1HCAR2ADRA1APDE4D | |
| Ethylene SCHEMBL27854424 | 0.90 | TSHR (0.50) | TSHRALDH1A1HCAR2ADRA1APDE4D | |
| Ammonia Solution, Strong SCHEMBL28141794 | 0.90 | TSHR (0.50) | TSHRALDH1A1HCAR2ADRA1APDE4D | |
| Water SCHEMBL27744037 | 0.90 | TSHR (0.50) | TSHRALDH1A1HCAR2ADRA1APDE4D | |
| SCHEMBL3838892 | 0.90 | TSHR (0.50) | TSHRALDH1A1HCAR2ADRA1APDE4D | |
| Fluoride SCHEMBL28010993 | 0.90 | TSHR (0.50) | TSHRALDH1A1HCAR2ADRA1APDE4D | |
| Trimethylammonium SCHEMBL21714443 | 0.86 | TSHR (0.46) | TSHRALDH1A1HCAR2ADRA1APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487084-B1 | Image forming method and apparatus | CANON KK (JP) | 2002-01-30 | — | — | EP | disclosed |
| US-5864406-A | Method and apparatus for forming halftone images on organic-silver-salt-based printing plates | CANON KABUSHIKI KAISHA (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0487084-A2 | Image forming method and apparatus | CANON KABUSHIKI KAISHA (JP) | 1992-05-27 | — | — | EP | disclosed |