SCHEMBL7518704

SCHEMBL7518704

NC(=O)C(O)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7522704 1.00
SCHEMBL7520162 1.00
SCHEMBL6375136 0.78
SCHEMBL3855225 0.77
SCHEMBL12696702 0.71
SCHEMBL16312548 0.71
SCHEMBL4107937 0.71
SCHEMBL2570646 0.71
SCHEMBL2569280 0.71
SCHEMBL294878 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3943152-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed
EP-2809156-B1 ALLOSTERIC MODULATORS OF 5-HYDROXYTRYPTAMINE 2C RECEPTOR (5-HT2CR) UNIV TEXAS (US) 2017-05-24 EP disclosed
US-9533973-B2 Allosteric modulators of 5-hydroxytryptamine 2C receptor (5-HT2CR) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2017-01-03 US disclosed
EP-2809156-A2 ALLOSTERIC MODULATORS OF 5-HYDROXYTRYPTAMINE 2C RECEPTOR (5-HT2CR) The Board of Regents of The University of Texas System (US) 2014-12-10 EP disclosed
US-20140336375-A1 ALLOSTERIC MODULATORS OF 5-HYDROXYTRYPTAMINE 2C RECEPTOR (5-HT2CR) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-11-13 US disclosed
WO-2013086266-A2 ALLOSTERIC MODULATORS OF 5-HYDROXYTRYPTAMINE 2C RECEPTOR (5-HT2CR) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-06-13 WO disclosed
CN-101234996-B Green synthesis method for ketazine UNIV ZHEJIANG TECHNOLOGY 2012-01-25 CN disclosed
CN-101234996-A Green synthesis method for ketazine UNIV ZHEJIANG TECHNOLOGY (CN) 2008-08-06 CN disclosed
US-20020042055-A1 Alteration of hydrolase genes and screening of the resulting libraries for the ability to catalyze specific reactions MAXYGEN, INC. 2002-04-11 US disclosed
WO-2001046476-A1 ALTERATION OF HYDROLASE GENES AND SCREENING OF THE RESULTING LIBRARIES FOR THE ABILITY TO CATALYZE SPECIFIC REACTIONS MAXYGEN, INC. (US) 2001-06-28 WO disclosed
US-3943152-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US disclosed