⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731430 | 0.92 | — | — | |
| SCHEMBL15355904 | 0.89 | — | — | |
| SCHEMBL4868455 | 0.89 | — | — | |
| SCHEMBL8446362 | 0.89 | — | — | |
| SCHEMBL8449434 | 0.89 | — | — | |
| SCHEMBL14265378 | 0.85 | — | — | |
| SCHEMBL12373201 | 0.83 | — | — | |
| SCHEMBL17585384 | 0.83 | — | — | |
| SCHEMBL12929773 | 0.83 | — | — | |
| SCHEMBL13535228 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138288-B2 | Synthesis of cationic siloxane prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2012-03-20 | — | — | US | disclosed |
| US-20110146206-A1 | SYNTHESIS OF CATIONIC SILOXANE PREPOLYMERS | TECHNOLAS PERFECT VISION GMBH (DE) | 2011-06-23 | — | — | US | disclosed |
| US-7951897-B2 | reacting a bis-haloalkyl polydimethylsiloxane with alkyl functionalized hydroxy secondary amine 2-(methylamino)ethanol, to form a reaction product, reacting with methacrylating agent to form second intermediate, quaternizing with a halomethane. to form cationic polymer; implant, contact lenses | BAUSCH & LOMB INCORPORATED (US) | 2011-05-31 | — | — | US | disclosed |
| US-20080182956-A1 | SYNTHESIS OF CATIONIC SILOXANE PREPOLYMERS | SANTARUS, INC. | 2008-07-31 | — | — | US | disclosed |
| EP-0676437-B1 | USE OF POLYCATIONIC POLYMER AS BACTERICIDAL/ALGICIDAL AGENT | SAGAMI CHEM RES (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5616317-A | HETEROCYCLIC NITROGEN POLYMER | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0676437-A1 | POLYCATIONIC POLYMER AND POLYCATIONIC BACTERICIDAL/ALGICIDAL AGENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-10-11 | — | — | EP | disclosed |
| US-4587321-A | Polyquaternary polysiloxane polymers | L'OREAL (FR) | 1986-05-06 | — | — | US | disclosed |
| US-4533714-A | CATIONIC POLYMERS;COSMETICS;HAIR CONDITIONERS;SHAMPOO;RINSING | L'OREAL (FR) | 1985-08-06 | — | — | US | disclosed |