SCHEMBL7519459

SCHEMBL7519459

Cc1cc(C)[nH]n1.Cc1n[nH]c(C)c1C([SiH3])(c1c(C)n[nH]c1C)c1c(C)n[nH]c1C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
DYRK1A Q13627 1/20 0.34
ADORA2A P29274 2/20 0.32
ADORA2B P29275 2/20 0.32
DAO P14920 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
PDE10A Q9Y233 1/20 0.31
CHEK1 O14757 1/20 0.31
AKT2 P31751 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALPL P05186 1/20 0.30
ALK Q9UM73 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903302 0.84 DYRK1A (0.46) TSHRDYRK1AADORA2AADORA2BCHEK1
SCHEMBL1503 0.76
SCHEMBL29150915 0.73
Potassium SCHEMBL30471622 0.73
SCHEMBL30802139 0.73
SCHEMBL28959328 0.73 HCAR2 (0.44) TSHRDYRK1ADAOHCAR2PDE10A
SCHEMBL30404482 0.73
SCHEMBL28852463 0.73 HCAR2 (0.44) TSHRDYRK1ADAOHCAR2PDE10A
SCHEMBL28054863 0.73
SCHEMBL28068910 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165568-A4 METAL COMPOUNDS CONTAINING NEUTRAL, MULTIDENTATE AZACYCLIC LIGANDS, CATALYSTS USING THEM, OLEFIN POLYMERIZATION METHODS USING THEM EQUISTAR CHEM LP (US) 2002-10-16 EP disclosed
EP-1165568-A1 METAL COMPOUNDS CONTAINING NEUTRAL, MULTIDENTATE AZACYCLIC LIGANDS, CATALYSTS USING THEM, OLEFIN POLYMERIZATION METHODS USING THEM Equistar Chemicals L.P. (US) 2002-01-02 EP disclosed
WO-2000059914-A1 METAL COMPOUNDS CONTAINING NEUTRAL, MULTIDENTATE AZACYCLIC LIGANDS, CATALYSTS USING THEM, OLEFIN POLYMERIZATION METHODS USING THEM EQUISTAR CHEMICALS, L.P. (US) 2000-10-12 WO disclosed