SCHEMBL7519561

SCHEMBL7519561

O=C(O)Oc1ccc2cc(O)ccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.53
MEN1 O00255 8/20 0.53
MAPT P10636 2/20 0.53
NPC1 O15118 2/20 0.52
RAB9A P51151 1/20 0.52
ESR1 P03372 7/20 0.51
ESR2 Q92731 5/20 0.51
CASP3 P42574 2/20 0.51
SENP8 Q96LD8 2/20 0.51
SENP7 Q9BQF6 2/20 0.51
SENP6 Q9GZR1 2/20 0.51
PKM P14618 1/20 0.51
TDP1 Q9NUW8 2/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 2/20 0.46
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HIF1A Q16665 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809274 0.89 KMT2A (0.55) KMT2AMEN1MAPTTDP1TSHR
SCHEMBL7120446 0.86 CYP3A4 (0.63) KMT2AMEN1MAPTNPC1ESR1
SCHEMBL4423206 0.85 KMT2A (0.57) KMT2AMEN1MAPTNPC1ESR1
SCHEMBL11298874 0.85 KMT2A (0.52) KMT2AMEN1MAPTTDP1TSHR
SCHEMBL8604907 0.83 KMT2A (0.47) KMT2AMEN1MAPTNPC1ESR1
SCHEMBL21881870 0.82 CYP3A4 (0.59) KMT2AMEN1MAPTNPC1ESR1
SCHEMBL14579720 0.82 CYP3A4 (0.59) KMT2AMEN1MAPTNPC1ESR1
Naphthalene SCHEMBL1131780 0.81 KMT2A (0.69) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL1563903 0.81 KMT2A (0.69) KMT2AMEN1MAPTTDP1CYP1A2
SCHEMBL29937281 0.81 KMT2A (0.69) KMT2AMEN1MAPTTDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0803492-B1 METHOD FOR SEPARATING AND PURIFYING HYDROXYNAPHTHALENECARBOXYLIC ACIDS UENO SEIYAKU OYO KENKYUJO KK (JP) 2002-02-06 EP claimed
EP-0324373-B1 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AG (DE) 1993-12-08 EP claimed
EP-0324372-B1 WATER SOLUBLE 2-NAPHTHOL AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP claimed
EP-0502893-A1 AZO COMPOUNDS AND THEIR USE AS DYES, 1-SULPHO-6-CARBOXYL-AMINO NAPHTHALINE, ITS USE AS A DIAZO COMPONENT AND PROCESS FOR THE PRODUCTION OF THESE COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-16 EP claimed
WO-1991008265-A1 AZO COMPOUNDS AND THEIR USE AS DYES, 1-SULPHO-6-CARBOXYL-AMINO NAPHTHALINE, ITS USE AS A DIAZO COMPONENT AND PROCESS FOR THE PRODUCTION OF THESE COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-13 WO claimed
EP-0324372-A2 Water soluble 2-naphthol azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-19 EP claimed
EP-0324373-A2 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-19 EP claimed
EP-0324378-A2 Process for producing magnetic head of floating type SANYO ELECTRIC CO., LTD. (JP) 1989-07-19 EP claimed
EP-0316722-A2 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP claimed
EP-0513053-B1 PROCESS AND DEVICE FOR PRODUCING 2-HYDROXY-NAPHTHALENE-6-CARBOXYLIC ACID HOECHST AG (DE) 1994-10-19 EP disclosed
EP-0614947-A1 Water-soluble copper complexes of monoazo naphtol-carborylic acids, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-14 EP disclosed
EP-0507801-B1 AZO COMPOUNDS, PROCESS FOR PRODUCING THEM AND THEIR USE AS COLORANTS HOECHST AG (DE) 1994-08-10 EP disclosed
EP-0507822-B1 AZO COMPOUNDS, PROCESS FOR PRODUCING THEM AND THEIR USE AS DYES HOECHST AG (DE) 1994-06-22 EP disclosed
EP-0324373-B1 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AG (DE) 1993-12-08 EP disclosed
EP-0379856-A2 Process for metallising moulded polyarylene sulfide articles BAYER AG (DE) 1990-08-01 EP disclosed
EP-0325925-A1 Method for the purification of 2-hydroxy-naphthalene-6-carboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-02 EP disclosed
EP-0324372-A2 Water soluble 2-naphthol azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-19 EP disclosed
EP-0324373-A2 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-19 EP disclosed
EP-0316722-A2 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed
EP-0292955-A2 Water soluble monoazo naphtol carbonic acid compounds, process for their preparation and their use as dyes HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-30 EP disclosed