Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 3/20 | 0.47 |
| ▸ | GBA1 | P04062 | 9/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5122898 | 0.95 | MAPT (0.56) | MAPTNPSR1PRKCIGBA1PDE5A | |
| SCHEMBL7514104 | 0.91 | MAPT (0.54) | MAPTNPSR1GBA1PDE5AKDM4E | |
| SCHEMBL7519905 | 0.90 | PRKCI (0.58) | MAPTNPSR1PRKCIPDE5AKDM4E | |
| SCHEMBL7614371 | 0.90 | PRKCI (0.51) | MAPTNPSR1PRKCIGBA1PDE5A | |
| SCHEMBL5812312 | 0.88 | PRKCI (0.43) | MAPTNPSR1PRKCIPDE5AKDM4E | |
| SCHEMBL5125323 | 0.88 | MAPT (0.57) | MAPTNPSR1GBA1PDE5AKDM4E | |
| SCHEMBL5808881 | 0.87 | MAPT (0.56) | MAPTNPSR1PRKCIGBA1PDE5A | |
| SCHEMBL5123618 | 0.87 | MAPT (0.68) | MAPTNPSR1PRKCIGBA1PDE5A | |
| SCHEMBL7513594 | 0.86 | MAPT (0.49) | MAPTNPSR1GBA1PDE5AKDM4E | |
| SCHEMBL5129771 | 0.86 | MAPT (0.57) | MAPTNPSR1GBA1PDE5AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998006722-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |