Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | F11 | P03951 | 5/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | F9 | P00740 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077558 | 1.00 | F2 (0.59) | F2CYP3A4F11PRSS1F9 | |
| Hydrochloric Acid SCHEMBL6079137 | 0.99 | F2 (0.59) | F2CYP3A4F11PRSS1F9 | |
| SCHEMBL6077346 | 0.97 | F2 (0.59) | F2CYP3A4F11PRSS1F9 | |
| Hydrochloric Acid SCHEMBL23452302 | 0.94 | F2 (0.63) | F2CYP3A4F11PRSS1F9 | |
| Hydrochloric Acid SCHEMBL29880369 | 0.94 | F2 (0.63) | F2CYP3A4F11PRSS1F9 | |
| Hydrochloric Acid SCHEMBL6077587 | 0.94 | F2 (0.63) | F2CYP3A4F11PRSS1F9 | |
| Hydrochloric Acid SCHEMBL23452298 | 0.94 | F2 (0.63) | F2CYP3A4F11PRSS1F9 | |
| Trifluoroacetic Acid SCHEMBL29881048 | 0.89 | F2 (0.60) | F2CYP3A4F11PRSS1F9 | |
| SCHEMBL6077679 | 0.88 | F2 (0.47) | F2CYP3A4F11PRSS1F9 | |
| SCHEMBL6078027 | 0.88 | F2 (0.59) | F2CYP3A4F11PRSS1F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064559-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |