Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17552177 | 0.90 | MAPT (0.64) | MAPTGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL28439562 | 0.83 | MAPT (0.65) | MAPTGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL4711326 | 0.81 | MAPT (0.63) | MAPTGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL30471577 | 0.80 | MAPT (0.57) | MAPTGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL17552174 | 0.80 | MAPT (0.57) | MAPTGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL7748081 | 0.80 | MAPT (0.57) | MAPTGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL29831415 | 0.80 | MAPT (0.57) | MAPTGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL29911065 | 0.78 | MAPT (0.60) | MAPTGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL17552179 | 0.78 | MAPT (0.60) | MAPTGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL13609775 | 0.77 | MAPT (0.58) | MAPTGAAALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944600-B1 | PROCESS FOR CONVERTING HYDROXY HETEROAROMATICS TO ARYLAMINES | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-6034241-A | Process for converting hydroxy heteroaromatics to arylamines | HOECHST MARION ROUSSEL INC. (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0944600-A1 | PROCESS FOR CONVERTING HYDROXY HETEROAROMATICS TO ARYLAMINES | HOECHST MARION ROUSSEL, INC. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023589-A1 | PROCESS FOR CONVERTING HYDROXY HETEROAROMATICS TO ARYLAMINES | HOECHST MARION ROUSSEL, INC. (US) | 1998-06-04 | — | — | WO | disclosed |