Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564225 | 0.85 | GAA (0.52) | KMT2AMEN1GAAALDH1A1LMNA | |
| SCHEMBL2288515 | 0.84 | KMT2A (0.56) | KMT2AESR1ESR2MEN1GPR88 | |
| SCHEMBL18381730 | 0.84 | KMT2A (0.60) | KMT2AMEN1GAAALDH1A1LMNA | |
| SCHEMBL18381729 | 0.84 | KMT2A (0.60) | KMT2AMEN1GAAALDH1A1LMNA | |
| SCHEMBL174166 | 0.84 | KMT2A (0.60) | KMT2AMEN1GAAALDH1A1LMNA | |
| SCHEMBL29425354 | 0.84 | KMT2A (0.60) | KMT2AMEN1GAAALDH1A1LMNA | |
| SCHEMBL13684889 | 0.83 | KMT2A (0.55) | KMT2AESR1ESR2MEN1GPR88 | |
| SCHEMBL5257603 | 0.83 | KMT2A (0.55) | KMT2AESR1ESR2MEN1GAA | |
| SCHEMBL1094245 | 0.83 | KMT2A (0.55) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL10768637 | 0.83 | KMT2A (0.59) | KMT2AESR1ESR2MEN1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1353689-A | Novel hydroxamic acid derivatives | DAIICHI PREC KAGAKU (JP) | 2002-06-12 | — | — | CN | disclosed |
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| CN-1284060-A | Novel metalloprotease inhibitors | FUJI YAKUHIN KOGYO KK (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |