Sugi Predict

Sugi Predict / Compounds / SCHEMBL7520127

SCHEMBL7520127

SCHEMBL7520127

CCN(CC)c1ccc(N=Nc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 7/20 0.67
▸ MEN1 O00255 6/20 0.67
▸ POLB P06746 6/20 0.67
▸ NPC1 O15118 4/20 0.67
▸ TRPA1 O75762 1/20 0.56
▸ MAPT P10636 10/20 0.49
▸ RAB9A P51151 3/20 0.49
▸ KDM4E B2RXH2 3/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ LMNA P02545 2/20 0.49
▸ TDP1 Q9NUW8 2/20 0.49
▸ MAPK1 P28482 3/20 0.49
▸ GAA P10253 3/20 0.47
▸ NOX1 Q9Y5S8 2/20 0.47
▸ MCL1 Q07820 1/20 0.47
▸ RARB P10826 1/20 0.47
▸ RARG P13631 1/20 0.47
▸ ALDH1A1 P00352 5/20 0.47
▸ THRB P10828 2/20 0.47
▸ PKM P14618 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18243834 1.00 KMT2A (0.67) KMT2AMEN1POLBNPC1TRPA1
SCHEMBL18821811 1.00 KMT2A (0.67) KMT2AMEN1POLBNPC1TRPA1
SCHEMBL18821759 0.91 KMT2A (0.59) KMT2AMEN1POLBNPC1TRPA1
SCHEMBL20569230 0.89 KMT2A (0.58) KMT2AMEN1POLBNPC1TRPA1
SCHEMBL20569227 0.89 KMT2A (0.58) KMT2AMEN1POLBNPC1TRPA1
SCHEMBL64440 0.89 MEN1 (0.56) KMT2AMEN1POLBNPC1MAPT
SCHEMBL13297190 0.89 KMT2A (0.53) KMT2AMEN1POLBNPC1TRPA1
Hydrochloric Acid SCHEMBL2121314 0.87 MAPT (0.54) KMT2AMEN1POLBNPC1MAPT
SCHEMBL25284157 0.86 MAPT (0.67) KMT2AMEN1POLBNPC1MAPT
SCHEMBL18405934 0.86 MAPT (0.67) KMT2AMEN1POLBNPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001018017-A9 METHODS FOR DETECTING AND ENUMERATING CAMPYLOBACTER JEJUNI IN ENVIRONMENTAL SAMPLES AND FOR IDENTIFYING ANTIBIOTIC-RESISTANT STRAINS UNIV MICHIGAN STATE (US) 2002-09-26 — — WO claimed
US-10280181-B2 Coloring composition, anisotropic light absorption film, laminate, polarizing plate, image display device and compound FUJIFILM CORPORATION (JP) 2019-05-07 — — US disclosed
US-20160340367-A1 COLORING COMPOSITION, ANISOTROPIC LIGHT ABSORPTION FILM, LAMINATE, POLARIZING PLATE, IMAGE DISPLAY DEVICE AND COMPOUND FUJIFILM CORPORATION (JP) 2016-11-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160340367-A1 COLORING COMPOSITION, ANISOTROPIC LIGHT ABSORPTION FILM, LAMINATE, POLARIZING PLATE, IMAGE DISPLAY DEVICE AND COMPOUND AHR, CTNNA1, HTR1D KMT2A 1478/4885MEN1 168/4885POLB 3900/4885
US-10280181-B2 Coloring composition, anisotropic light absorption film, laminate, polarizing plate, image display device and compound AHR, CTNNA1, HTR1D KMT2A 1478/4885MEN1 168/4885POLB 3900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.