Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520724 | 0.94 | ADORA1 (0.45) | ADORA1ABCB1MAPTMEN1KMT2A | |
| SCHEMBL7519817 | 0.81 | ADORA1 (0.42) | ADORA1ABCB1MAPTMEN1KMT2A | |
| SCHEMBL7529881 | 0.81 | NT5E (0.39) | ABCB1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL6049948 | 0.78 | ADORA1 (0.51) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5837548 | 0.78 | ADORA1 (0.51) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7520721 | 0.77 | ADORA1 (0.42) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7519830 | 0.77 | ADORA1 (0.43) | ADORA1ABCB1MAPTMEN1KMT2A | |
| SCHEMBL6049995 | 0.77 | ADORA1 (0.43) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5837710 | 0.77 | ADORA1 (0.43) | ADORA1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6049849 | 0.76 | NT5E (0.38) | ABCB1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPN1, PTPRO, PTPRS | ADORA1 1492/4885ABCB1 1327/4885MAPT 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.