Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517922 | 1.00 | TDP1 (0.50) | TDP1TP53TSHRLMNAL3MBTL1 | |
| SCHEMBL7517916 | 1.00 | TDP1 (0.50) | TDP1TP53TSHRLMNAL3MBTL1 | |
| SCHEMBL7519566 | 1.00 | TDP1 (0.50) | TDP1TP53TSHRLMNAL3MBTL1 | |
| SCHEMBL7524986 | 0.93 | TDP1 (0.50) | TDP1TP53TSHRLMNAL3MBTL1 | |
| SCHEMBL7519725 | 0.93 | TDP1 (0.50) | TDP1TP53TSHRLMNAL3MBTL1 | |
| SCHEMBL7529071 | 0.93 | TDP1 (0.50) | TDP1TP53TSHRLMNAL3MBTL1 | |
| SCHEMBL7528153 | 0.93 | TDP1 (0.50) | TDP1TP53TSHRLMNAL3MBTL1 | |
| SCHEMBL3418666 | 0.91 | — | — | |
| SCHEMBL7519130 | 0.88 | TP53 (0.63) | TDP1TP53TSHR | |
| SCHEMBL3421460 | 0.88 | TSHR (0.41) | TDP1TP53TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020042055-A1 | Alteration of hydrolase genes and screening of the resulting libraries for the ability to catalyze specific reactions | MAXYGEN, INC. | 2002-04-11 | — | — | US | disclosed |
| WO-2001046476-A1 | ALTERATION OF HYDROLASE GENES AND SCREENING OF THE RESULTING LIBRARIES FOR THE ABILITY TO CATALYZE SPECIFIC REACTIONS | MAXYGEN, INC. (US) | 2001-06-28 | — | — | WO | disclosed |