Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.37 |
| ▸ | NPC1 | O15118 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484 | 0.86 | — | — | |
| SCHEMBL448177 | 0.86 | — | — | |
| SCHEMBL6067699 | 0.86 | NPC1 (0.39) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL27739673 | 0.84 | NPC1 (0.38) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL28213575 | 0.84 | NPC1 (0.38) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL28084257 | 0.84 | — | — | |
| SCHEMBL10782006 | 0.80 | NPC1 (0.36) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL28228685 | 0.71 | MEN1 (0.31) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL28181377 | 0.70 | NPC1 (0.30) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL28120417 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894898-B2 | Water-based ink for ink-jet recording and ink container | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2021-01-19 | — | — | US | disclosed |
| US-20180282563-A1 | Water-Based Ink for Ink-Jet Recording and Ink Container | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2018-10-04 | — | — | US | disclosed |
| US-9056997-B2 | Ink-jet recording apparatus, ink-jet recording method, recorded matter and composite black | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20150116392-A1 | Ink-Jet Recording Apparatus, Ink-Jet Recording Method, Recorded Matter and Composite Black | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2015-04-30 | — | — | US | disclosed |
| US-8632629-B2 | Water-based ink set for ink-jet recording, ink-jet recording method, and ink-jet recording apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8603232-B2 | Water-based ink set for ink-jet recording, ink-jet recording method, and ink-jet recording apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2013-12-10 | — | — | US | disclosed |
| US-8460449-B2 | Water-based ink set for ink jet recording, ink cartridge, and ink-jet recording apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2013-06-11 | — | — | US | disclosed |
| US-8449664-B2 | Water-based ink for ink-jet recording, ink cartridge, and ink-jet recording apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2013-05-28 | — | — | US | disclosed |
| US-8277549-B2 | Water-based ink for ink-jet recording, ink set for ink-jet recording, ink-jet recording apparatus, method of ink-jet recording, color change inhibitor, and method of suppressing color change | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2012-10-02 | — | — | US | disclosed |
| US-8252103-B2 | Water-based ink for ink-jet recording, ink cartridge, and ink-jet recording apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20110128333-A1 | Water-Based Ink Set for Ink Jet Recording, Ink Cartridge, and Ink-Jet Recording Apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2011-06-02 | — | — | US | disclosed |
| US-20110128332-A1 | Water-Based Ink for Ink-Jet Recording, Ink Cartridge, and Ink-Jet Recording Apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2011-06-02 | — | — | US | disclosed |
| EP-2327748-A1 | Water-based ink for ink-jet recording, ink cartridge, and ink-jet recording apparatus | Brother Kogyo Kabushiki Kaisha (JP) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327749-A1 | Water-based ink set for ink jet recording, ink cartridge, and ink-jet recording apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2011-06-01 | — | — | EP | disclosed |
| US-20100101450-A1 | Water-Based Black Ink for Ink-Jet Recording, Ink Cartridge, and Ink-Jet Recording Apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100101451-A1 | Water-Based Ink for Ink-Jet Recording, Ink Cartridge, and Ink-Jet Recording Apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100104756-A1 | Water-Based Ink for Ink-Jet Recording, Ink Set for Ink-Jet Recording, Ink-Jet Recording Apparatus, Method of Ink-Jet Recording, Color Change Inhibitor, and Method of Suppressing Color Change | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20090165673-A1 | Water-Based Ink for Ink-Jet Recording, Ink Cartridge and Ink-Jet Recording Apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090167831-A1 | Water-Based Ink for Ink-Jet Recording, Ink Cartridge and Ink-Jet Recording Apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090165671-A1 | Water-Based Ink For Ink-Jet Recording, Ink Cartridge and Ink-Jet Recording Apparatus | BROTHER KOGYO KABUSHIKI KAISHA (JP) | 2009-07-02 | — | — | US | disclosed |