Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467310 | 0.89 | HSP90AA1 (0.53) | HSP90AA1CA2CA4CA5AALOX15 | |
| SCHEMBL814 | 0.85 | HSP90AA1 (0.59) | HSP90AA1CA2CA4CA5AALOX15 | |
| SCHEMBL5077624 | 0.82 | MAPT (0.64) | HSP90AA1ALDH1A1MAPTPLIN1LMNA | |
| SCHEMBL5077621 | 0.82 | MAPT (0.64) | HSP90AA1ALDH1A1MAPTPLIN1LMNA | |
| SCHEMBL23757989 | 0.81 | HSP90AA1 (0.55) | HSP90AA1CA2CA4CA5AALOX15 | |
| SCHEMBL28824440 | 0.81 | HSP90AA1 (0.55) | HSP90AA1CA2CA4CA5AALOX15 | |
| SCHEMBL11252036 | 0.81 | HSP90AA1 (0.55) | HSP90AA1CA2CA4CA5AALOX15 | |
| SCHEMBL5694513 | 0.81 | HSP90AA1 (0.55) | HSP90AA1CA2CA4CA5AALOX15 | |
| SCHEMBL1508 | 0.81 | HSP90AA1 (0.55) | HSP90AA1CA2CA4CA5AALOX15 | |
| SCHEMBL19033787 | 0.79 | HSP90AA1 (0.63) | HSP90AA1CA2CA4CA5ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0872466-B1 | Process for the synthesis of 1,7-diaryl or 1,7-heteroarylheptan-4-ols and synthetic intermediates | FABBRICA ITALIANA SINTETICI SPA (IT) | 2002-01-30 | — | — | EP | disclosed |
| US-5973157-A | Process for the synthesis of 1,7-diarly or heteroaryl-heptane-4-ols and new synthetic intermediates | F.I.S. FABBRICA ILTALIANA SINTETICI S.P.A. (IT) | 1999-10-26 | — | — | US | disclosed |