Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 11/20 | 0.68 |
| ▸ | CSNK2B | P67870 | 11/20 | 0.68 |
| ▸ | CSNK2A1 | P68400 | 11/20 | 0.68 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.44 |
| ▸ | PRKCG | P05129 | 2/20 | 0.44 |
| ▸ | PRKCB | P05771 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | PRKCH | P24723 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 2/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.44 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.44 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522608 | 0.81 | CSNK2A2 (0.97) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG | |
| SCHEMBL11921344 | 0.81 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG | |
| SCHEMBL12775847 | 0.81 | CSNK2A2 (0.68) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG | |
| SCHEMBL7526635 | 0.71 | CSNK2A2 (0.57) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG | |
| SCHEMBL7525774 | 0.71 | CSNK2A2 (0.66) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG | |
| Hydrochloric Acid SCHEMBL7240577 | 0.68 | CSNK2A2 (0.54) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG | |
| SCHEMBL12775879 | 0.65 | CFTR (0.64) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG | |
| SCHEMBL12775848 | 0.61 | CSNK2A2 (0.68) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG | |
| SCHEMBL11921339 | 0.61 | CSNK2A2 (0.97) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG | |
| SCHEMBL5738619 | 0.61 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937044-B1 | CFTR CHANNEL ACTIVATOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NAT RECH SCIENT (FR) | 2002-01-30 | — | — | EP | disclosed |
| EP-0937044-A1 | CFTR CHANNEL ACTIVATOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998005642-A1 | CFTR CHANNEL ACTIVATOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-02-12 | — | — | WO | disclosed |