Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22562829 | 0.81 | ABL1 (0.59) | ABL1BCRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL9967714 | 0.79 | ABL1 (0.61) | ABL1BCRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL11301276 | 0.77 | ABL1 (0.54) | ABL1BCRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL17843663 | 0.76 | ABL1 (0.80) | ABL1BCRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL16372856 | 0.76 | ABL1 (0.80) | ABL1BCRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL9123339 | 0.76 | ABL1 (0.58) | ABL1BCRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL9123345 | 0.76 | ABL1 (0.58) | ABL1BCRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL5016906 | 0.75 | TUBB1 (0.56) | ABL1BCRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL5016909 | 0.75 | TUBB1 (0.56) | ABL1BCRCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL15397238 | 0.73 | ABL1 (0.54) | ABL1BCRCYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218370-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001025227-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-04-12 | — | — | WO | disclosed |