Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478262 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL7522732 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3677890 | 0.89 | CHRM2 (0.37) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3672454 | 0.87 | SLC18A3 (0.38) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3672453 | 0.87 | SLC18A3 (0.38) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL3672027 | 0.84 | NSD2 (0.39) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL2534761 | 0.81 | CHRM2 (0.44) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL2534764 | 0.81 | CHRM2 (0.44) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL14341426 | 0.81 | MAPT (0.37) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL5585364 | 0.78 | MAPT (0.31) | MAPTGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1182205-A1 | Chiral diphosphines via 2,3 -sigmatropic rearrangement.Application in asymmetric transition metal catalysis | PPG-Sipsy S.C.A. (FR) | 2002-02-27 | — | — | EP | disclosed |