Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350353 | 0.79 | KMT2A (0.49) | MCL1BCL2L1KMT2ASIRT5STAT3 | |
| SCHEMBL20999134 | 0.77 | BCL2L1 (0.53) | MCL1BCL2L1KMT2ASIRT5STAT3 | |
| SCHEMBL4653744 | 0.75 | TRPV1 (0.46) | MCL1BCL2L1HSD17B10POLBTSHR | |
| SCHEMBL4653741 | 0.75 | TRPV1 (0.46) | MCL1BCL2L1HSD17B10POLBTSHR | |
| SCHEMBL5961640 | 0.75 | BCL2L1 (0.52) | MCL1BCL2L1KMT2ASIRT5STAT3 | |
| SCHEMBL12862656 | 0.74 | BCL2L1 (0.58) | MCL1BCL2L1KMT2ASIRT5STAT3 | |
| SCHEMBL155359 | 0.73 | KMT2A (0.53) | MCL1BCL2L1KMT2APKMALDH1A1 | |
| SCHEMBL3299042 | 0.73 | KDM4C (0.56) | MCL1BCL2L1KMT2ASIRT5STAT3 | |
| SCHEMBL24107347 | 0.73 | MCL1 (0.50) | MCL1BCL2L1KMT2ASIRT5STAT3 | |
| SCHEMBL7529550 | 0.73 | KMT2A (0.56) | KMT2ASIRT5STAT3CTDSP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288731-A | Antiemetics, antiserotonine agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-02-22 | — | — | US | disclosed |
| WO-1992009284-A1 | 2,6-METHANO-2H-1-BENZOXOCINCARBOXAMIDES AS 5-HT3-ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1989010364-A1 | DIBENZOFURANCARBOXAMIDES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-11-02 | — | — | WO | disclosed |